Nearly impossible to to differentiate Lyme from other bacteria ticks transfer during a bite (Co-infections) a trained LLMD (Lyme literate Md) will devise a treatment plan that best fits what disease you may carry. The following are some of the symptoms experienced with the most common co-infections (there are more than on this list - see link at bottom and not listed here, viral co-infections) This is not to replace medical evaluation and treatment from your MD. ~~~~~~~~~~~~~~~~~~~~~~~ Chart of symptom break-down of Lyme and co-infections:http://www.lyme-symptoms.com/LymeCoinfectionChart.html
Babesiosis is a malaria-like protozoa illness that invades, infects, and kills the red blood cells. Symptoms include fatigue, night sweats, chills, fever, shortness of breath, heart palpitations, headache, dark urine, muscle pain, joint pain, nausea, and jaundice. Treatment is an anti-malarial combined with an antibiotic--often Mepron or Malarone with Zithromax or Biaxin w/Artemisinin. Septra/Bactrim has shown in some cases to be effective.
Ehrlichiosis is a bacterial infection that invades and infects the white blood cells. There are two types of Ehrlichiosis: Human Monocytic Ehrlichiosis (HME) and Human Granulocytic Ehrlichiosis (HGE). Symptoms include malaise, fever, sweating, nausea, dry cough, headache, anemia, muscle aches and pain. First line treatment is most often Doxycycline, Minocycline and/or Rifampin. Cipro, Levaquin, Biaxin and Azithromycin have shown in some cases to be effective.
Bartonella also known as cat-scratch fever is a bacterial infection. Symptoms include swollen, painful lymph nodes, muscle and/or joint pain, nausea, vomiting, chills, anxiety, insomnia, red rashes that resemble stretch marks. Treatment is often Levaquin or Rifampin, Biaxin or Azithromycin. Septra/Bactrim has shown in some cases to be effective.
Mycoplasma is a bacterial infection. Symptoms include fatigue, breathing problems, headache, muscle pain and soreness, nausea, lymph node pain, and cognitive problems. Treatment is usually Doxycycline, Minocycline, Azithromycin, Clarithromycin, or Ciprofloxacin.
Lyme Disease - (300 strains worldwide - 100 strains in the U.S.) In addition their are 3 bacterial forms of LD that must be addressed before treatment ends, Bacterial Forms include: Spirochete, Cyst, Cell Wall Deficient To learn more on the 3 forms please read this:http://www.lymebook.com/top10forms
~~~~~~~~~~~~~~~~~~~~~~~~ CO-INFECTIONS SYMPTOMS (SCROLL DOWN FOR LYME SYMPTOMS) The following info was gathered from a Lyme conference ILADS LLMD during his presentation:
Bartonella Brain Fog Fever Foot/heel pain Ice pick headaches Photophobia Tachycardia Bowel problems IBS/IBD Swollen Glands OCD behavior Anxiety Endocarditis Retinitis Peripheral Neuropathy Rapid relapse off abx Immediate illness following tick bite Subcutaneous nodules Swollen Joints Swollen lymph nodes Psychiatric problems Shin pain No response to previous abx Plantar and costal margin pain (plantar=soles of feet costal margin = The lower edge of the chest (thorax) formed by the bottom edge of the rib cage) Rapid mood shifts Development of these symptoms during Babesia Treatment
Ehrlichia (There are 2 known strains of Ehrlichia - HME and HGE) Fatigue Myalgias (muscle pain) Tendon pain Mild headaches Fevers Right upper quad pain Elevated Liver function (after ruling out hepatitis)
A website shows these symptoms for Ehrlichia and/or Anaplasma: Ehrlichiosis Human granulocytic Ehrlichiosis (HGE) is caused by Anaplasma phagocytophila. Human monocytic Ehrlichiosis (HME) is caused by Ehrlichia chaffeensis. Symptoms: Fever (only after initial infection) Myalgia and arthralgia Headcache Lycopenia and thrombocytopenia Hyponatremia Mental confusion Skin rashes Genital and oral ulcers Severe pain syndromes Nausea and vomiting (acute flare-ups) *Natural Therapy recommendations (see Buhner's book): think astragalus (elevates interferon gamma) and colchicine
Mycoplasma Fermentans Fatigue Fever Insommnia Headache Bowel problems Joint swelling and pain No response to previous abx
Babesia Bradycardia (Slowed heart beat) Headaches Night sweats Fever Dry cough Air hunger Easy bruising Tinnitus Rage Despair Chills Flushing Vivid or violent dreams Dysphagia (Difficulty swallowing) Psychic Phenomena Severe Neurological illness Thirst/Polydipsia (excessive thirst) Fatigue Rheumatoid Arthritis Severe nausea Malaise (A vague feeling of bodily discomfort) Anemia Thrombocytosis (Increased numbers of platelets in the blood) Thrombocytopenia (A decrease in the number of platelets in the blood, resulting in the potential for increased bleeding and decreased ability for clotting)
In the book "Diagnoses and Treatment of Babesia" by Dr. Schaller he lists the following as Babesia symptoms: • High fevers • Dullness • Listless • Chills • Sweats • Headaches • Fatigue • Sleep more than 8 1/2 hours per day
Bladder dysfunction Brain fog Bradycardia Burning or stabbing sensations Cardiac impairment Change in bowel function Chest pain Confusion Depression Difficulty thinking Difficulty with concentration and reading Difficulty with speech, writing Difficulty finding words; name blocking Disorientation: getting lost, going to wrong places Disturbed sleep: too much, too little, fractionated, early awakening Ears/Hearing: buzzing, ringing, ear pain, sound sensitivity Exaggerated symptoms or worse hangover from alcohol Eyes/Vision: double, blurry, increased floaters, light sensitivity Facial paralysis (Bell's palsy) Fatigue, tiredness, poor stamina Forgetfulness Headache Heart block Heart murmur Heart palpitations Heart valve prolapse Increased motion sickness Irritability Irritable bladder Joint pain or swelling Lightheadedness Migrating pain Mood swings Muscle pain or cramps Neck creaks & cracks Neck stiffness, pain Numbness Pelvic pain Poor attention Poor balance Poor short-term memory Problem absorbing new information Pulse skips Rib soreness Sexual dysfunction or loss of libido Shooting pains Shortness of breath; cough Skin hypersensitivity Sore throat Stiffness of the joints or back Swollen glands Testicular pain Tingling Transitory symptoms - (i.e., shoulder pain for awhile, then possibly stomach pain, then knee pain, any combo ever-changing, shifting or moving) Tremor Twitching of the face or other muscles Unavoidable need to sit or lay down Unexplained breast pain Unexplained fevers, sweats, chills or flushing Unexplained hair loss Unexplained menstrual irregularity' Unexplained milk production Unexplained weight loss or gain Upset Stomach or abdominal pain Vertigo Wooziness
~~~~~~~~~~~~~~~~~~~ Lyme symptoms from Canlyme
Rash at site of bite Rashes on other parts of your body Rash basically circular and spreading out (or generalized) Raised rash, disappearing and recurring
Head, Face, Neck
Unexplained hair loss Headache, mild or severe, Seizures Pressure in Head, White Matter Lesions in Head (MRI) Twitching of facial or other muscles Facial paralysis (Bell's Palsy) Tingling of nose, (tip of) tongue, cheek or facial flushing Stiff or painful neck Jaw pain or stiffness Dental problems (unexplained) Sore throat, clearing throat a lot, phlegm ( flem ), hoarseness, runny nose
Double or blurry vision Increased floating spots Pain in eyes, or swelling around eyes Oversensitivity to light Flashing lights/Peripheral waves/phantom images in corner of eyes
Decreased hearing in one or both ears, plugged ears Buzzing in ears Pain in ears, oversensitivity to sounds Ringing in one or both ears
Digestive and Excretory Systems
Diarrhea Constipation Irritable bladder (trouble starting, stopping) or Interstitial cystitis Upset stomach (nausea or pain) or GERD (gastroesophageal reflux disease)
Bone pain, joint pain or swelling, carpal tunnel syndrome Stiffness of joints, back, neck, tennis elbow Muscle pain or cramps, (Fibromyalgia)
Respiratory and Circulatory Systems
Shortness of breath, can't get full/satisfying breath, cough Chest pain or rib soreness Night sweats or unexplained chills Heart palpitations or extra beats Endocarditis, Heart blockage
Tremors or unexplained shaking Burning or stabbing sensations in the body Fatigue, Chronic Fatigue Syndrome, Weakness, peripheral neuropathy or partial paralysis Pressure in the head Numbness in body, tingling, pinpricks Poor balance, dizziness, difficulty walking Increased motion sickness Lightheadedness, wooziness
Mood swings, irritability, bi-polar disorder Unusual depression Disorientation (getting or feeling lost) Feeling as if you are losing your mind Over-emotional reactions, crying easily Too much sleep, or insomnia Difficulty falling or staying asleep Narcolepsy, sleep apnea Panic attacks, anxiety
Memory loss (short or long term) Confusion, difficulty in thinking Difficulty with concentration or reading Going to the wrong place Speech difficulty (slurred or slow) Stammering speech Forgetting how to perform simple tasks
Reproduction and Sexuality
Loss of sex drive Sexual dysfunction Unexplained menstral pain, irregularity Unexplained breast pain, discharge Testicular or pelvic pain
Unexplained weight gain, loss Extreme fatigue Swollen glands/lymph nodes Unexplained fevers (high or low grade) Continual infections (sinus, kidney, eye, etc.) Symptoms seem to change, come and go Pain migrates (moves) to different body parts Early on, experienced a "flu-like" illness, after which you have not since felt well. Low body temperature Allergies/Chemical sensitivities Increased effect from alcohol and possible worse hangover
CLASSIC LYME (Bb infection)- · Gradual onset of initial (viral-like) symptoms- this often makes it difficult to pinpoint when the infection began. · Multisystem- almost always, in disseminated stages, involves more than one part or system (i.e. joint pain plus cognitive dysfunction). · Migratory- first a knee will hurt, then over time this may lessen and the elbow or shoulder acts up, and later the joints calm down but headaches worsen. · Stiff joints and loud joint crepitus, especially the neck (“Lyme shrug”). · Headaches are often nuchal and associated with stiff, painful and crepitant neck. · Afternoon fevers, often unnoticed- most Lyme patients have subnormal temperatures in the AM but rise to 99+ by early to mid-afternoon. No obvious sweats. · Tiredness and limited stamina- often is a strong need to rest or even nap in the afternoon, especially when the flushed face and elevated temperature appears. · 4-week cycles- Bb activity, and thus symptoms, wax and wane in a cycle that repeats roughly every four weeks. This cycle, if clear, can guide your treatments. · Slow response to treatment, with an initial symptom flare in most (“Herxheimer-like reaction”) then improvement over weeks, punctuated by the monthly symptom flares. Likewise, if treatment is ended too soon, an initial period of well-being will gradually, over a few weeks, be replaced by a return of symptoms. · EM rash in 25% to 50%
BARTONELLA & ”BARTONELLA-LIKE ORGANISMS”- · Gradual onset of initial illness. · CNS symptoms are out of proportion to the musculoskeletal ones- if a patient has no or minimal joint complaints but is severely encephalopathic (see below), then think of Bartonella/BLO. · Obvious signs of CNS irritability can include muscle twitches, tremors, insomnia, seizures, agitation, anxiety, severe mood swings, outbursts and antisocial behavior. · GI involvement may present as gastritis or abdominal pain (mesenteric adenitis). · Sore soles, especially in the morning. · Tender sub-cutaneous nodules along the extremities, especially outer thigh, shins, and occasionally along the triceps. · Occasional lymphadenopathy. · Morning fevers, usually around 99. Occasionally light sweats are noted. · Elevated vascular endothelial growth factor (VEGF) occurs in a minority, but the degree of elevation correlates with activity of the infection and may be used to monitor treatment. · Rapid response to treatment changes- often symptoms improve within days after antibiotics are begun, but relapses occur also within days if medication is withdrawn early. · May have papular or linear red rashes (like stretch marks that do not always follow skin planes), especially in those with GI involvement.
BABESIA SPECIES- · Rapid onset of initial illness, often with sudden onset of high fever, severe headaches, sweats and fatigue, thus it is easy to know when infection began. · Obvious sweats, usually at night, but can be day sweats as well. · Air hunger, need to sigh and take a deep breath; dry cough without apparent reason. · Headaches can be severe - dull, global (involves the whole head, described like the head is in a vise). · Fatigue is prominent, does not clear with rest, and is made worse with exercise. · Mental dullness and slowing of reactions and responses. · Dizziness- more like a tippy feeling, and not vertigo or purely orthostasis. · Symptoms cycle rapidly, with flares every four to six days. · Hypercoaguable states are often associated with Babesia infections. · Rarely, splenomegaly · Very severe Lyme Disease can be a clue to Babesia infection, as it will make Lyme symptoms worse and Lyme treatments less effective.
EHRLICHIA/ANAPLASMA- · Rapid onset of initial illness with fever, headache, prostration. · Headaches are sharp, knife-like, and often behind the eyes. · Muscle pain, not joint pain, and can be mild or severe. · Low WBC count, elevated liver enzymes, and (rarely) inclusions seen in the WBCs. · Rarely see diffuse vasculitic rash, including palms and soles (less than 10%). · Rapid response to treatment.
DNA VIRUSES (HHV-6, EBV, CMV) · Persistent fatigue, made worse with exercise. · Sore throat, lymphadenopathy, and other viral-like complaints. · May see elevated liver enzymes and low WBC counts. · Autonomic dysfunction.
___Joint pain and stiffness (often both Left and Right sides as opposed to Lyme which is often on one side only with pain and stiffness that changes locations)
___Muscle pains especially the calves; may be twitching and cramping also
___Foot pain, more in the morning involving the heels or soles of the feet (sometimes misdiagnosed as plantar fasciitis)
___Nerve irritation symptoms which can be described as burning, vibrating, numb, shooting, etc.
___Tremors and/or muscle twitching
___Heart palpitations and strange chest pains
___Episodes of breathlessness
___Strange rashes recurring on the body often, red stretch marks, and peculiar tender lumps and nodules along the sides of the legs or arms, spider veins
___Gastrointestinal symptoms, abdominal pain and acid reflux
___Shin bone pain and tenderness
Bartonella is a bacterium that causes illness, the most commonly known of which is a disease called "Cat Scratch Fever." Thousands of known cases of Bartonella occur in the U.S. each Year, with the vast majority of known cases due to bites from fleas that infest cats or infected dogs (may also occur directly from bites and scratches from infected dogs or cats). Bartonella can also be transmitted by ticks that transmit Lyme Disease. In fact, in a study published recently, deer ticks from New Jersey had a higher prevalence of Bartonella organisms than of Lyme organisms.
It is unclear whether the organism that we see transmitted along with Lyme disease is actually a Bartonella species (such as B. henselae or B. quintana) or is "Bartonella-Like Organism" (BLO) that is yet to be fully identified. While BLO has features similar to organisms in the Bartonella family, it also has features slimiar to the Mycoplasma and the Francisella (causes tularemia) families.
As with other co-infections, there is a lot of overlap of symptoms between Lyme disease and Babesiosis. An accumulation of the following signs and symptoms probably warrant testing and/or treatment of Babesiosis:
___Fatigue and often excessive sleepiness
___High fever at onset of illness
___Night sweats that are often drenching and profuse
___Severe muscle pains, especially the large muscles of the legs (quads, buttocks, etc.)
___Neurological symptoms often described as "dizzy, tipsy, and spaciness," similar to a sensation of "floating" or "walking off the top of a mountain onto a cloud"
___Episodes of breathlessness, "air hunger", and/or cough
___Decreased appetite and/or nausea
___Spleen and/or liver enlargement
___Abnormal labs (low white blood count, low platelet counts, mild elevation of liver enzymes, and elevated sed rate)
___Headaches (migraine-like, persistent, and especially involving the back of the head and upper neck areas)
___Joint pain (more common with Lyme and Bartonella)
___anxiety/panic (more common with Bartonella)
___Lymph gland swelling (more common with Bartonella and Lyme)
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