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 Post subject: Lab that bills all insurance & has low cost for no insur
PostPosted: Mon Feb 18, 2008 2:34 pm 
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This was sent to me and I found it interesting. However, I do not know if their testing compares to Igenex. The flier explains the Lyme test and reliability. You can also call them with any questions.

Copy of flier from CENTRAL FLORIDA RESEARCH, INC. - see bottom for billing, contact and pricing info.
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

CENTRAL FLORIDA RESEARCH, INC.

WHAT IS LYME DISEASE?
Lyme disease is caused by a spirochetal bacteria,
Borrelia burgdorferi ( Bb). The bacteria Bb is transmitted by ticks and other vectors including mosquitoes, fleas and mites. A recent study at the University of New Haven in Connecticut revealed that ticks tested carried not only Bb, but Babesia, Ehrlichia, Bartonella, Rocky Mountain Spotted Fever, Rickettsia, Mycoplasma and other pathogenic agents. The results of this study were almost identical to another study done on the West Coast.

WHAT ARE THE SYMPTOMS ?
Most physicians look for the accepted tell-tale Bull's Eye rash (EM) seen at the site of a bite. Studies have shown that the rash has appeared in approximately 40% of the patients infected. Therefore, a Lyme diagnosis is complicated. A physician should look for the most common symptoms of Lyme disease, which include flu-like symptoms, fever, general aches and pains, stiff neck, swollen glands and fatigue.

Called 'The Great Imitator ' Lyme disease mimics many other diseases. Two of the most common misdiagnosis are Chronic Fatigue and Fibromyalgia. The symptoms of autoimmune disease like RA, MS, ALS and Lupus often overlap Lyme disease symptoms. Neurological, Neuropsychiatric, Cardiac Pulmonary and Gastrointestinal problems appear to develop if the disease goes untreated and the infection is allowed to progress.

To better understand the complicated issues in the diagnosis of Lyme Disease, we recommend you read the essay, " When To Suspect Lyme Disease" by John D. Bleiweiss, M.D. The essay is posted on the Lifelyme website: http://www.lifelyme.org

HOW IS LYME DISEASE DIAGNOSED?
According to the Center for Disease Control ( CDC ) Lyme is a clinical diagnosis, which means a physician may make a diagnosis based on your health history and your present symptoms. However, laboratory tests are usually part of a reported diagnosis.

WHAT TESTS ARE AVAILABLE ?
Basically there are two types of Lyme test, antibody tests and antigen tests. The ELISA and Western Blot are both antibody tests. Although the Western Blot is more sensitive than the ELISA, not all patients may be producing antibodies at the time these tests are taken. Therefore, in the absences of antibodies, these test may report a false negative. Antibody tests measure the presence of the antibodies, IgM and/or IgG in a patent's blood.

The Rapid Antigen Identification of 'Bb by Flow Cytometry' test from the Central Florida Research lab detects the actual antigen (Bb) in the blood. An antigen test checks for the organism itself and is not dependent upon a sick immune system's ability to produce antibodies against the invading bacteria Bb. Therefore, antigen tests appear to be more reliable. Our blood supply is protected from HIV by an antigen test. Prior to the time of an antigen test being developed for checking the blood for HIV, when an antibody test was depended upon many cases of HIV slipped by as the patient were not producing antibody to HIV. Since the Red Cross started using as antigen test this has not occurred. Again, this is due to the fact that a test that is capable of picking up the organism itself is more reliable than a test which is dependent upon the bodies ability to produce antibodies.
HOW DOES THE 'Bb BY FLOW ' TEST WORK?
The Central Florida Research test, the 'Bb by Flow '(Rapid
Antigen Identification by Flow Cytometry ) is a one of a kind
test. It is an immune fluorescence test using a special kind
of machine called a Flow Cytometer. A Flow Cytometer is a
specific instrument designed to identify the various stages
or forms of Bb, which includes the cysts. Cells acting with
fluorescent antibodies that only adhere to the Bb antigen
identify the Bb antigen and these are counted. The Flow
Cytometer can count the number of organisms in 100,000
cells in three minutes and 50,000 cells in one minute. It
counts all the cells passing through the aperture and
enumerates the organisms that react with the fluorescent
antibody. The test result will be reported as a percent of the
counted cells. The Flow Cytometer used by CFR has been
specifically modified to pick up an organism as small as the
spirochete that causes Lyme Disease.

The Flow Cytometer prints out in a percentage ratio of how many
cells are enumerated and fluorescing. The results are expressed
as .02 negative .03 borderline .04 positive. The Borrelia burgdorferi
Direct Fluorescent Antigen test by Flow Cytometer is the most
definitive test of its kind available today.

HOW DOES THE LYME BACTERIA Bb EVADE THE
IMMUNE SYSTEM?

Understanding the microbiology behind the cyst or cell wall deficient
( CWD) form of Bb and its ability to hide from the immune system
helps us understand the Lyme disease controversies and the complications
in testing for the bacteria.

At the beginning of the last century, bacteriologist entered into an intense
debate over pleomorphism. Pleomorphism is the ability of a bacteria to
change from one form to another and as in the case of Bb, back again into
its original form. The debate split microbiologist into two camps: the
monomorphists and the pleomorphists. The monomorphists believe that
each bacterial cell by binary fission divides transversely to produce two
new cells which evolve to replicate the original cell in size and shape.
The pleomorphists believe that even common bacteria show complex life
cycles, and have the ability to shed their cell wall.

In the Spring of 2006, a research study was published on "A Life Cycle for
Borrelia Spirochetes', by Dr. Alan MacDonald, Ph.D., What is a Bb life cycle?
According to Dr. MacDonald's study the "....life cycles are diverse arrays of
life forms which emerge in an ordered sequence, which are 'connected' to one
another across primary and secondary hosts, and constitute a cycle with
'circular' relationship between hosts."

Upon entering the body Bb in its spirochetal form cloaks itself with a coating
of the person's own DNA. The system which is normally in Cellular Immunity
recognizes that there is a foreign invader and goes into Humoral Immunity,
the state of attack. The invader due to its ability to cloak itself and hide from
the immune system evades detection. Hence, the referral to the spirochete as
being a Stealth Pathogen. The white blood cells, the Neutrophils and Macrophages,
whose job it is to engulf foreign pathogenic invasion, allows the cloaked spirochetes
to go in and out of these cells as they don't recognize it as the enemy. They see
it as 'self' ( part of the person's own DNA).



WHAT HAPPENS WHEN THE IMMUNE SYSTEM DOESN'T RECOGNIZE THE LYME BACTERIA Bb AS AN INVADER?
Under these circumstances, the immune system stays in Humoral Immunity Overdrive, due to the fact that it can't locate the invader and destroy it. Normally, when an enemy is destroyed the immune system returns to normal Cellular Immunity. When an immune system is left in Humoral Immunity Overdrive, the results are negative. Autoimmune issues occur and the immune system starts to attack many systems in the body. It is not unusual to see people with Borrelia or Mycoplasma infections exhibiting autoimmune issues such as diagnosed in Lupus, Parkinson's ALS, Lupus, RA and MS. Chronic Fatigue Immune Dysfunction ( CFIDS) and or Fibromyalgiia are other common misdiagnosis. Specific diagnosis is the result of a combination of factors present in the individual. These include the general health of the individual's immune system, their genetics, and the infectious agent. There are over 300 strains of Bb, and many species, therefore combinations of symptoms vary in each individual, which requires the expertise of a Lyme knowledgeable physician in order to successfully treat a patient.

WHO DOES THE INSTRUMENT FLOW CYTOMETRY WORK?

The Flow Cytometer can count the numbers of organisms in 100,000 events ( cells) in 2 minutes and 50,000 in 1 munute. To visually count
the organism in 100,000 events or 50,000 event using a microscope would be almost an impossibility. The Flow Cytometer counts the number of all events passing throught the aperture and enumerates the organisms that react with the antibody used to identify the antigen. The test result will be reported as a percentage of the counted events. This instrument has the ability to read the various stages of the spirochete which is the causative agent of Lyme Disease.

HOW DO I ORDER THE "Bb BY FLOW" ( Central Florida Research Antigen Identification test for Bb by Flow Cytometry) TEST?
Any physician/practitioner who is licensed by the state in which they practice can order this test for you.

HOW DOES THE TESTING PROCESS WORK?
The physician can order the collection kit online by accessing the ORDER KIT FORM on the CFR website.

When the blood sample is drawn it is returned to the lab in the prepaid mailer by FedEx overnight for processing. The results are sent to your physician/practitioner's office within 72 hours from the time the lab receives the blood.

Blood samples are accepted Monday through Friday. Please do not send bloods for delivery on weekends.

WHAT IS THE COST OF THE "Bb BY FLOW" TEST?
Central Florida Research, Inc. is pleased to announce that effective immediately we are able to accept billing for both Medicare and major insurance carriers for our testing.





We feel that this change will make it possible for many more people to be tested for the bacteria than ever in the past.

The cost of testing for the "Bb by Flow" test for those individuals that do not have insurance coverage has been reduced to $200.00.

CENTRAL FLORIDA RESEARCH, INC.
http://www.centralfloridaresearch.com
Tom Long, Director
245 N. Seminole Avenue
Lake Alfred, Florida 33850

Mailing Address:
P. O. Box 599
Lake Alfred, Florida 33850
Phone Number: (863) 956-3538
Fax Number: (863) 956-0839

_________________
~~~~~~~~~~~~~~~~~~~~~~
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Always check w/your MD regarding advice given by me or any member at this forum & any articles & info. at this site. Site disclaimer: viewtopic.php?f=6&t=16


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