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 Post subject: Different forms of Lyme and co-infection treatments
PostPosted: Mon Feb 18, 2008 3:25 pm 
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This information was obtained from the Hope to Heal Lyme Conference 2006.
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Lyme - Various Forms and Antibiotic Treatments


Borrelia Burgdorferi has the following forms & treatments:
• Spirochete form which has a cell wall and may be treated with penicillins, cephalosporins, Primaxin, or Vancomycin
• L-Form which has no cell wall and may be treated with Tetracyclines and Erythromycins.
• Cyst form - Metronidazole (Flagyl) and Tinidazole, possibly Rifampin

Antibiotics that do rely on cell walls for killing can kill the spirochete but not the L-Form. Drugs like penicillin works on a cell wall and needs to be at a sustained level for 72 hours. Peaks and valleys allow the germs to recover. Doxycycline does not require a sustained level. It may be more effective at 400mg once per day via IV than 100mg four times per day orally. The germs live inside and outside the cells. Erythromycin can get to the intracellular bugs. Probenecid can make the antibiotics work better. The body pumps the Probenecid out of the kidney but leaves the antibiotics. Zithromax is only intracellular. However, it is not a good drug for Lyme. Biaxin is a much better drug. Ketek is by far the best. May be 10x better than IV Rocephin but it is hard on the liver and the heart. People usually have a difficult time and may herx for 1-2 months. It is killing germs that have never been killed before. The tetracyclines, unless used at very high levels, do not kill the bugs - they only suppress. They are also sometimes difficult to tolerate. Tinidazole is only slightly better tolerated than Flagyl. Rifampin is an old TB drug that may work on all three forms of Borrelia. Bicillin shots 3-4 times a week (better IM for yeast issues). May also be useful as an IV. Can add Biaxin, Ketek, or Flagyl.

Co-infections, normally are treated first because they can keep the Bb alive in a sense, they all work together.

For more on co-infections and treatments visit or read below: http://www.lymeinfo.net/coinfectionarticle.html

Compiled By: Melanie Reber

Babesiosis
Explanation: Protozoa that invade, infect, and kill the red blood cells
Symptoms: Fatigue, night sweats, fever, chills, weakness, weight loss, nausea, abdominal pain, diarrhea, cough, shortness of breath, headache, neck and back stiffness, dark urine or blood in urine
Treatment: Atovaquone (Mepron) plus Azithromycin (Zithromax), Clindamycin and oral Quinine
Other: Alternative treatment may include Riamet or Artemisinin

Bartonella
Explanation: Bartonella spp. bacterium
Symptoms: Fever, chills, headache and severe pain in the tibia, weight loss, sore throat, papular or angiomatous rash
Treatment: Erythromycin, plus a Fluoroquinolone or Rifampin

Ehrlichiosis (HGE and HME)
Explanation: Rickettsiae that infect the white blood cells
Symptoms: Anemia, fever, chills, headache, muscle pain, rigors, gastrointestinal symptoms, anorexia, fatigue
Treatment: Doxycycline, Rifampin

Rocky Mountain spotted fever
Explanation: Rickettsia rickettsii parasite that invades the cells lining the heart and blood vessels
Symptoms: High fever, severe headache (especially behind the eyes), maculopapular skin rash
Treatment: Tetracycline, Doxycycline, or Chloramphenicol

Colorado Tick Fever
Explanation: Reovirus that lodges inside the cells
Symptoms: High fever, chills, severe muscle aches, back pain, headache (especially behind the eyes), light sensitivities, nausea, vomiting, diarrhea
Treatment: No antiviral therapy is available
Other: Aspirin

Relapsing Fever
Explanation: Borrelia hermsii spirochete
Symptoms: High fever, sudden chills, eye inflammation, coughing, jaundice, petechial rash
Treatment: Tetracycline, Doxycycline, or Chloramphenicol

Tularemia
Explanation: Francisella tularensis bacterium
Symptoms: Painful and swollen lymph nodes, fever, chills, fatigue
Treatment: Tetracycline, Chloramphenicol

Powassan encephalitis
Explanation: Flavivirus that invades and infects the brain
Symptoms: Fever, headache, pain behind the eyes, light sensitivity, muscle weakness, seizures, paralysis, brain inflammation
Treatment: No effective treatment (more info here: http://cmr.asm.org/cgi/content/full/13/1/67#SEC1_3 )

Tick Paralysis
Explanation: A toxic reaction to saliva from female ticks
Symptoms: Paralysis begins in legs and spreads throughout the body within hours
Treatment: Recovery is rapid following the removal of the tick

Mycoplasma
Explanation: A genus of small bacteria which lack cell walls. M. fermentans, M. pneumoniae, M. penetrans, M. hominis and M. genetalium
Symptoms: Fatigue, headaches, muscle pain and soreness, nausea, gastrointestinal problems, joint pain and soreness, lymph node pain, cognitive problems, depression, breathing problems and other signs and symptoms
Treatment: Slow-growing mycoplasmal infections are not rapidly susceptible to antibiotics. Doxycycline, Minocycline, Ciprofloxacin, Azithromycin, and Clarithromycin may be used.

Links of interest:
http://www.lymeinfo.net/coinfectionarticle.html

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